Feasibility, Long-term Safety and Immune Monitoring of Regulatory T Cell Therapy in Living Donor Kidney Transplant Recipients

Short-term outcomes in kidney transplantation are marred by progressive transplant failure and mortality secondary to immunosuppression toxicity. Immune modulation with autologous polyclonal regulatory T cell (Treg) remedy might facilitate immunosuppression discount selling higher long-term scientific outcomes.

In a Phase I scientific trial, 12 kidney transplant recipients acquired 1-10×10⁶ Treg per kg at Day+5 put up transplantation in lieu of induction immunosuppression (Treg Therapy cohort). Nineteen sufferers acquired customary immunosuppression (Reference cohort). Primary outcomes have been rejection-free and affected person survival. Patient and Transplant survival was 100%; acute rejection-free survival was 100% in the Treg Therapy vs 78.9% in the reference cohort at 48 months post-transplant.

Treg remedy revealed no extra security issues. Four sufferers in the Treg Therapy cohort had mycophenolate mofetil withdrawn efficiently and stay on tacrolimus monotherapy. Treg infusion resulted in a long-lasting dose-dependent improve in peripheral blood Tregs along with a rise in marginal zone B cell numbers. We recognized a pre-transplantation immune phenotype suggesting a excessive threat of unsuccessful ex-vivo Treg enlargement.

Autologous Treg remedy is possible, protected and is probably related to a decrease rejection price than customary immunosuppression. Treg remedy might present an thrilling alternative to attenuate immunosuppression remedy and enhance long-term outcomes.

Immune thrombocytopenia (ITP) World Impact Survey (I-WISh): affected person and doctor perceptions of prognosis, indicators and signs, and remedy

Immune thrombocytopenia (ITP) is now well-known to cut back sufferers’ health-related-quality-of-life. However, knowledge describing which indicators and signs sufferers and physicians understand as having the best impression are restricted, as is knowing the total results of ITP therapies. I-WISh (ITP World Impact Survey) was an exploratory, cross-sectional survey designed to determine the multifaceted impression of ITP, and its therapies, on sufferers’ lives.

It centered on perceptions of 1507 sufferers and 472 physicians from 13 international locations concerning diagnostic pathway, frequency and severity of indicators and signs, and remedy use. Twenty-two p.c of sufferers skilled delayed prognosis (attributable to a number of components), 73% of whom felt anxious in consequence.

Patients rated fatigue among the many most frequent, extreme symptom related to ITP at prognosis (58% most frequent; 73% most extreme), though physicians assigned it decrease precedence (30%). Fatigue was one of the few signs persisting at survey completion (50% and 65%, respectively) and was the highest symptom sufferers wished resolved (46%). Participating physicians have been skilled at treating ITP, thereby recognizing the necessity to restrict corticosteroid use to newly-diagnosed or first-relapse sufferers and espoused elevated use of thrombopoietin receptor agonists and anti-CD20 after relapse in sufferers with persistent/continual illness.

Patient and physicians have been largely aligned on prognosis, signs, and remedy use. I-WISh demonstrated that sufferers and physicians largely align on total ITP symptom burden, with sure variations eg fatigue. Understanding the emotional and scientific toll of ITP on the affected person will facilitate shared decision-management, setting and institution of remedy targets and illness stage-appropriate remedy choice.

Co-Culture System of Human Enteroids/Colonoids with Innate Immune Cells

Human intestinal enteroids derived from grownup stem cells supply a related ex vivo system to review organic processes of the human intestine. They recreate mobile and practical options of the intestinal epithelium of the small gut (enteroids) or colon (colonoids) albeit restricted by the dearth of related cell sorts that assist keep tissue homeostasis and reply to exterior challenges.

In the intestine, innate immune cells work together with the epithelium, assist barrier operate, and deploy effector features. We have established a co-culture system of enteroid/colonoid monolayers and underlying macrophages and polymorphonuclear neutrophils to recapitulate the mobile framework of the human intestinal epithelial area of interest. Enteroids are generated from biopsies or resected tissue from any phase of the human intestine and maintained in long-term cultures as three-dimensional buildings by means of supplementation of stem cell progress components.

Immune cells are remoted from contemporary human complete blood or frozen peripheral blood mononuclear cells (PBMC). Monocytes from PBMC are differentiated into macrophages by cytokine stimulation previous to co-culture. The strategies are divided into the 2 primary parts of the mannequin: (1) producing enteroid/colonoid monolayers and isolating immune cells and (2) meeting of enteroid/colonoid-immune cell co-cultures with separate apical and basolateral compartments. Co-cultures containing macrophages could be maintained for 48 hr whereas these involving neutrophils, resulting from their shorter life span, stay viable for Four hr.

Enteroid-immune co-cultures allow a number of final result measures, together with transepithelial resistance, manufacturing of cytokines/chemokines, phenotypic evaluation of immune cells, tissue immunofluorescence imaging, protein or mRNA expression, antigen or microbe uptake, and different mobile features. © 2020 Wiley Periodicals LLC.

Autoimmune Regulator (AIRE) Antibody
20-abx175528	Abbexa	EUR 1479.60 EUR 710.40	1 mg 200 ug

Autoimmune Regulator (AIRE) Antibody
20-abx175529	Abbexa	EUR 1479.60 EUR 710.40	1 mg 200 ug

Autoimmune Regulator (AIRE) Antibody
abx117155-100ug	Abbexa	100 ug	EUR 560.4

Autoimmune Regulator (AIRE) Antibody
20-abx007582	Abbexa	EUR 360.00 EUR 526.80 EUR 226.80	100 ul 200 ul 30 ul

Autoimmune Regulator (AIRE) Antibody
20-abx001466	Abbexa	EUR 493.20 EUR 710.40 EUR 218.40 EUR 376.80	100 ul 200 ul 20 ul 50 ul

Autoimmune Regulator (AIRE) Antibody
abx019018-100ug	Abbexa	100 ug	EUR 410.4

Autoimmune Regulator (AIRE) Antibody
20-abx013298	Abbexa	EUR 376.80 EUR 117.60 EUR 477.60 EUR 594.00	100 ug 10 ug 200 ug 300 µg

Autoimmune Regulator (AIRE) Antibody
abx038141-100ug	Abbexa	100 ug	EUR 469.2

Autoimmune Regulator (AIRE) Antibody
abx230241-100ug	Abbexa	100 ug	EUR 577.2

Autoimmune Regulator (AIRE) Antibody
abx331461-100ul	Abbexa	100 ul	EUR 510

Autoimmune Regulator (AIRE) Antibody
20-abx312575	Abbexa	EUR 493.20 EUR 2214.00 EUR 718.80 EUR 218.40 EUR 360.00	100 ug 1 mg 200 ug 20 ug 50 ug

Autoimmune Regulator (AIRE) Antibody
20-abx323992	Abbexa	EUR 376.80 EUR 292.80	100 ug 50 ug

Autoimmune Regulator (AIRE) Antibody
20-abx325675	Abbexa	EUR 376.80 EUR 292.80	100 ug 50 ug

Human Autoimmune Regulator ELISA kit
E01A0527-192T	BlueGene	192 tests	EUR 1524
Description: A sandwich ELISA for quantitative measurement of Human Autoimmune Regulator in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Autoimmune Regulator ELISA kit
E01A0527-48	BlueGene	1 plate of 48 wells	EUR 624
Description: A sandwich ELISA for quantitative measurement of Human Autoimmune Regulator in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Autoimmune Regulator ELISA kit
E01A0527-96	BlueGene	1 plate of 96 wells	EUR 822
Description: A sandwich ELISA for quantitative measurement of Human Autoimmune Regulator in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Autoimmune Regulator ELISA kit
E02A0527-192T	BlueGene	192 tests	EUR 1524
Description: A sandwich ELISA for quantitative measurement of Rat Autoimmune Regulator in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Autoimmune Regulator ELISA kit
E02A0527-48	BlueGene	1 plate of 48 wells	EUR 624
Description: A sandwich ELISA for quantitative measurement of Rat Autoimmune Regulator in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Autoimmune Regulator ELISA kit
E02A0527-96	BlueGene	1 plate of 96 wells	EUR 822
Description: A sandwich ELISA for quantitative measurement of Rat Autoimmune Regulator in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Autoimmune Regulator ELISA kit
E07A0527-192T	BlueGene	192 tests	EUR 1524
Description: A sandwich ELISA for quantitative measurement of Porcine Autoimmune Regulator in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Autoimmune Regulator ELISA kit
E07A0527-48	BlueGene	1 plate of 48 wells	EUR 624
Description: A sandwich ELISA for quantitative measurement of Porcine Autoimmune Regulator in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Autoimmune Regulator ELISA kit
E07A0527-96	BlueGene	1 plate of 96 wells	EUR 822
Description: A sandwich ELISA for quantitative measurement of Porcine Autoimmune Regulator in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Autoimmune Regulator ELISA kit
E04A0527-192T	BlueGene	192 tests	EUR 1524
Description: A sandwich ELISA for quantitative measurement of Rabbit Autoimmune Regulator in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Autoimmune Regulator ELISA kit
E04A0527-48	BlueGene	1 plate of 48 wells	EUR 624
Description: A sandwich ELISA for quantitative measurement of Rabbit Autoimmune Regulator in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Autoimmune Regulator ELISA kit
E04A0527-96	BlueGene	1 plate of 96 wells	EUR 822
Description: A sandwich ELISA for quantitative measurement of Rabbit Autoimmune Regulator in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Autoimmune Regulator ELISA kit
E06A0527-192T	BlueGene	192 tests	EUR 1524
Description: A sandwich ELISA for quantitative measurement of Goat Autoimmune Regulator in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Autoimmune Regulator ELISA kit
E06A0527-48	BlueGene	1 plate of 48 wells	EUR 624
Description: A sandwich ELISA for quantitative measurement of Goat Autoimmune Regulator in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Autoimmune Regulator ELISA kit
E06A0527-96	BlueGene	1 plate of 96 wells	EUR 822
Description: A sandwich ELISA for quantitative measurement of Goat Autoimmune Regulator in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Autoimmune Regulator ELISA kit
E09A0527-192T	BlueGene	192 tests	EUR 1524
Description: A sandwich ELISA for quantitative measurement of Monkey Autoimmune Regulator in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Autoimmune Regulator ELISA kit
E09A0527-48	BlueGene	1 plate of 48 wells	EUR 624
Description: A sandwich ELISA for quantitative measurement of Monkey Autoimmune Regulator in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Autoimmune Regulator ELISA kit
E09A0527-96	BlueGene	1 plate of 96 wells	EUR 822
Description: A sandwich ELISA for quantitative measurement of Monkey Autoimmune Regulator in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Autoimmune Regulator ELISA kit
E08A0527-192T	BlueGene	192 tests	EUR 1524
Description: A sandwich ELISA for quantitative measurement of Canine Autoimmune Regulator in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Autoimmune Regulator ELISA kit
E08A0527-48	BlueGene	1 plate of 48 wells	EUR 624
Description: A sandwich ELISA for quantitative measurement of Canine Autoimmune Regulator in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Autoimmune Regulator ELISA kit
E08A0527-96	BlueGene	1 plate of 96 wells	EUR 822
Description: A sandwich ELISA for quantitative measurement of Canine Autoimmune Regulator in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Autoimmune Regulator ELISA kit
E03A0527-192T	BlueGene	192 tests	EUR 1524
Description: A sandwich ELISA for quantitative measurement of Mouse Autoimmune Regulator in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Autoimmune Regulator ELISA kit
E03A0527-48	BlueGene	1 plate of 48 wells	EUR 624
Description: A sandwich ELISA for quantitative measurement of Mouse Autoimmune Regulator in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Autoimmune Regulator ELISA kit
E03A0527-96	BlueGene	1 plate of 96 wells	EUR 822
Description: A sandwich ELISA for quantitative measurement of Mouse Autoimmune Regulator in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Autoimmune regulator (AIRE) Conjugated Antibody
C48129	SAB	100ul	EUR 476.4

Human Autoimmune Regulator (AIRE) Protein
20-abx652629	Abbexa	EUR 693.60 EUR 309.60 EUR 2064.00 EUR 828.00 EUR 510.00	100 ug 10 ug 1 mg 200 ug 50 ug

Mouse Autoimmune Regulator (AIRE) Protein
20-abx652630	Abbexa	EUR 693.60 EUR 309.60 EUR 2064.00 EUR 828.00 EUR 510.00	100 ug 10 ug 1 mg 200 ug 50 ug

Mouse Autoimmune Regulator (AIRE) Protein
20-abx652631	Abbexa	EUR 693.60 EUR 309.60 EUR 2064.00 EUR 828.00 EUR 510.00	100 ug 10 ug 1 mg 200 ug 50 ug

Autoimmune Regulator (AIRE) Antibody (HRP)
20-abx312576	Abbexa	EUR 493.20 EUR 2214.00 EUR 718.80 EUR 218.40 EUR 360.00	100 ug 1 mg 200 ug 20 ug 50 ug

Autoimmune Regulator (AIRE) Antibody (FITC)
20-abx312577	Abbexa	EUR 493.20 EUR 2214.00 EUR 718.80 EUR 218.40 EUR 360.00	100 ug 1 mg 200 ug 20 ug 50 ug

Autoimmune Regulator (AIRE) Antibody (Biotin)
20-abx312578	Abbexa	EUR 493.20 EUR 2214.00 EUR 718.80 EUR 218.40 EUR 360.00	100 ug 1 mg 200 ug 20 ug 50 ug

Human AIRE/ Autoimmune regulator ELISA Kit
E0100Hu	Sunlong	1 Kit	EUR 726

Human Autoimmune Regulator (AIRE) ELISA Kit
DLR-AIRE-Hu-48T	DL Develop	48T	EUR 620.4
Description: A sandwich quantitative ELISA assay kit for detection of Human Autoimmune Regulator (AIRE) in samples from tissue homogenates or other biological fluids.

Human Autoimmune Regulator (AIRE) ELISA Kit
DLR-AIRE-Hu-96T	DL Develop	96T	EUR 807.6
Description: A sandwich quantitative ELISA assay kit for detection of Human Autoimmune Regulator (AIRE) in samples from tissue homogenates or other biological fluids.

Mouse Autoimmune Regulator (AIRE) ELISA Kit
DLR-AIRE-Mu-48T	DL Develop	48T	EUR 632.4
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Autoimmune Regulator (AIRE) in samples from tissue homogenates or other biological fluids.

Mouse Autoimmune Regulator (AIRE) ELISA Kit
DLR-AIRE-Mu-96T	DL Develop	96T	EUR 825.6
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Autoimmune Regulator (AIRE) in samples from tissue homogenates or other biological fluids.

Guinea pig Autoimmune Regulator ELISA kit
E05A0527-192T	BlueGene	192 tests	EUR 1524
Description: A sandwich ELISA for quantitative measurement of Guinea pig Autoimmune Regulator in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig Autoimmune Regulator ELISA kit
E05A0527-48	BlueGene	1 plate of 48 wells	EUR 624
Description: A sandwich ELISA for quantitative measurement of Guinea pig Autoimmune Regulator in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig Autoimmune Regulator ELISA kit
E05A0527-96	BlueGene	1 plate of 96 wells	EUR 822
Description: A sandwich ELISA for quantitative measurement of Guinea pig Autoimmune Regulator in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

ELISA kit for Human Autoimmune regulator
EK3200	SAB	96 tests	EUR 663.6
Description: Enzyme-linked immunosorbent assay kit for quantification of Human Autoimmune regulator in samples from serum, plasma, tissue homogenates and other biological fluids.

Human Autoimmune Regulator (AIRE) ELISA Kit
20-abx150773	Abbexa	EUR 8853.60 EUR 4719.60 EUR 1093.20	10 × 96 tests 5 × 96 tests 96 tests

Mouse Autoimmune Regulator (AIRE) ELISA Kit
20-abx153694	Abbexa	EUR 8853.60 EUR 4719.60 EUR 1093.20	10 × 96 tests 5 × 96 tests 96 tests

Human Autoimmune Regulator (AIRE) CLIA Kit
abx196471-96tests	Abbexa	96 tests	EUR 990

Chicken Autoimmune Regulator (AIRE) ELISA Kit
abx355828-96tests	Abbexa	96 tests	EUR 990

Rabbit Autoimmune Regulator (AIRE) ELISA Kit
abx363707-96tests	Abbexa	96 tests	EUR 990

Monkey Autoimmune Regulator (AIRE) ELISA Kit
abx359019-96tests	Abbexa	96 tests	EUR 990

Pig Autoimmune Regulator (AIRE) ELISA Kit
abx360670-96tests	Abbexa	96 tests	EUR 990

Human Autoimmune Regulator (AIRE) ELISA Kit
abx570732-96tests	Abbexa	96 tests	EUR 848.4

Mouse Autoimmune Regulator (AIRE) ELISA Kit
abx570926-96tests	Abbexa	96 tests	EUR 886.8

Human Autoimmune Regulator (AIRE) CLIA Kit
20-abx493615	Abbexa	EUR 9567.60 EUR 5095.20 EUR 1177.20	10 × 96 tests 5 × 96 tests 96 tests

Mouse Autoimmune Regulator (AIRE) CLIA Kit
20-abx493616	Abbexa	EUR 9567.60 EUR 5095.20 EUR 1177.20	10 × 96 tests 5 × 96 tests 96 tests

Human Autoimmune Regulator (AIRE) ELISA Kit
abx250784-96tests	Abbexa	96 tests	EUR 848.4

Human AIRE(Autoimmune regulator) ELISA Kit
EH1501	FN Test	96T	EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml

Mouse Autoimmune regulator, Aire ELISA KIT
ELI-11972m	Lifescience Market	96 Tests	EUR 1038

Human Autoimmune regulator, AIRE ELISA KIT
ELI-12083h	Lifescience Market	96 Tests	EUR 988.8

Human Autoimmune Regulator (AIRE) ELISA Kit
RDR-AIRE-Hu-48Tests	Reddot Biotech	48 Tests	EUR 652.8

Human Autoimmune Regulator (AIRE) ELISA Kit
RDR-AIRE-Hu-96Tests	Reddot Biotech	96 Tests	EUR 907.2

Mouse Autoimmune Regulator (AIRE) ELISA Kit
RDR-AIRE-Mu-48Tests	Reddot Biotech	48 Tests	EUR 668.4

Mouse Autoimmune Regulator (AIRE) ELISA Kit
RDR-AIRE-Mu-96Tests	Reddot Biotech	96 Tests	EUR 928.8

Human Autoimmune Regulator(AIRE)ELISA Kit
QY-E00071	Qayee Biotechnology	96T	EUR 433.2

Human Autoimmune Regulator (AIRE) ELISA Kit
RD-AIRE-Hu-48Tests	Reddot Biotech	48 Tests	EUR 625.2

Human Autoimmune Regulator (AIRE) ELISA Kit
RD-AIRE-Hu-96Tests	Reddot Biotech	96 Tests	EUR 867.6

Mouse Autoimmune Regulator (AIRE) ELISA Kit
RD-AIRE-Mu-48Tests	Reddot Biotech	48 Tests	EUR 639.6

Mouse Autoimmune Regulator (AIRE) ELISA Kit
RD-AIRE-Mu-96Tests	Reddot Biotech	96 Tests	EUR 888

Human Autoimmune Regulator (AIRE) ELISA Kit
SEC322Hu-10x96wellstestplate	Cloud-Clone	10x96-wells test plate	EUR 5677.8
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Autoimmune Regulator (AIRE) in Tissue homogenates and other biological fluids.

Human Autoimmune Regulator (AIRE) ELISA Kit
SEC322Hu-1x48wellstestplate	Cloud-Clone	1x48-wells test plate	EUR 572.76
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Autoimmune Regulator (AIRE) in Tissue homogenates and other biological fluids.

Human Autoimmune Regulator (AIRE) ELISA Kit
SEC322Hu-1x96wellstestplate	Cloud-Clone	1x96-wells test plate	EUR 766.8
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Autoimmune Regulator (AIRE) in Tissue homogenates and other biological fluids.

Human Autoimmune Regulator (AIRE) ELISA Kit
SEC322Hu-5x96wellstestplate	Cloud-Clone	5x96-wells test plate	EUR 3090.6
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Autoimmune Regulator (AIRE) in Tissue homogenates and other biological fluids.

Human Autoimmune Regulator (AIRE) ELISA Kit
4-SEC322Hu	Cloud-Clone	EUR 5738.40 EUR 3031.20 EUR 768.00	10 plates of 96 wells 5 plates of 96 wells 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Autoimmune Regulator (AIRE) in samples from Tissue homogenates and other biological fluids. with no significant corss-reactivity with analogues from other species.

Mouse Autoimmune Regulator (AIRE) ELISA Kit
SEC322Mu-10x96wellstestplate	Cloud-Clone	10x96-wells test plate	EUR 5834.88
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Autoimmune Regulator (AIRE) in Tissue homogenates and other biological fluids.

Mouse Autoimmune Regulator (AIRE) ELISA Kit
SEC322Mu-1x48wellstestplate	Cloud-Clone	1x48-wells test plate	EUR 585.7
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Autoimmune Regulator (AIRE) in Tissue homogenates and other biological fluids.

Mouse Autoimmune Regulator (AIRE) ELISA Kit
SEC322Mu-1x96wellstestplate	Cloud-Clone	1x96-wells test plate	EUR 785.28
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Autoimmune Regulator (AIRE) in Tissue homogenates and other biological fluids.

Mouse Autoimmune Regulator (AIRE) ELISA Kit
SEC322Mu-5x96wellstestplate	Cloud-Clone	5x96-wells test plate	EUR 3173.76
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Autoimmune Regulator (AIRE) in Tissue homogenates and other biological fluids.

Mouse Autoimmune Regulator (AIRE) ELISA Kit
4-SEC322Mu	Cloud-Clone	EUR 5895.60 EUR 3114.00 EUR 786.00	10 plates of 96 wells 5 plates of 96 wells 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Mouse Autoimmune Regulator (AIRE) in samples from Tissue homogenates and other biological fluids. with no significant corss-reactivity with analogues from other species.

Rat Autoimmune regulator(AIRE)ELISA kit
YLA1691RA-48T	Shanghai YL Biotech	48T	EUR 465

Rat Autoimmune regulator(AIRE)ELISA kit
YLA1691RA-96T	Shanghai YL Biotech	96T	EUR 600

Human Autoimmune regulator(AIRE)ELISA kit
YLA4398HU-48T	Shanghai YL Biotech	48T	EUR 435

Human Autoimmune regulator(AIRE)ELISA kit
YLA4398HU-96T	Shanghai YL Biotech	96T	EUR 562.5

ELISA kit for Human AIRE (Autoimmune Regulator)
E-EL-H0536	Elabscience Biotech	1 plate of 96 wells	EUR 640.8
Description: A sandwich ELISA kit for quantitative measurement of Human AIRE (Autoimmune Regulator) in samples from Serum, Plasma, Cell supernatant

CLIA kit for Human AIRE (Autoimmune Regulator)
E-CL-H0428	Elabscience Biotech	1 plate of 96 wells	EUR 700.8
Description: A sandwich CLIA kit for quantitative measurement of Human AIRE (Autoimmune Regulator) in samples from Serum, Plasma, Cell supernatant

ELISA kit for Human AIRE (Autoimmune Regulator)
ELK3194	ELK Biotech	1 plate of 96 wells	EUR 518.4
Description: A sandwich ELISA kit for detection of Autoimmune Regulator from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

ELISA kit for Mouse AIRE (Autoimmune Regulator)
ELK6262	ELK Biotech	1 plate of 96 wells	EUR 518.4
Description: A sandwich ELISA kit for detection of Autoimmune Regulator from Mouse in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

Autoimmune Regulator Phospho-Ser156 (AIRE pS156) Antibody
20-abx012667	Abbexa	EUR 376.80 EUR 117.60 EUR 477.60 EUR 594.00	100 ug 10 ug 200 ug 300 µg

Guinea pig Autoimmune Regulator (AIRE) ELISA Kit
abx358142-96tests	Abbexa	96 tests	EUR 990

Autoimmune Regulator Phospho-Ser156 (AIRE pS156) Antibody
20-abx323993	Abbexa	EUR 376.80 EUR 292.80	100 ug 50 ug

ELISA kit for Human Autoimmune regulator (AIRE)
KTE60636-48T	Abbkine	48T	EUR 398.4
Description: Quantitative sandwich ELISA for measuring Human Autoimmune regulator (AIRE) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human Autoimmune regulator (AIRE)
KTE60636-5platesof96wells	Abbkine	5 plates of 96 wells	EUR 2538
Description: Quantitative sandwich ELISA for measuring Human Autoimmune regulator (AIRE) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human Autoimmune regulator (AIRE)
KTE60636-96T	Abbkine	96T	EUR 646.8
Description: Quantitative sandwich ELISA for measuring Human Autoimmune regulator (AIRE) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Mouse Autoimmune regulator (AIRE)
KTE70434-48T	Abbkine	48T	EUR 398.4
Description: Quantitative sandwich ELISA for measuring Mouse Autoimmune regulator (AIRE) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Mouse Autoimmune regulator (AIRE)
KTE70434-5platesof96wells	Abbkine	5 plates of 96 wells	EUR 2538
Description: Quantitative sandwich ELISA for measuring Mouse Autoimmune regulator (AIRE) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Mouse Autoimmune regulator (AIRE)
KTE70434-96T	Abbkine	96T	EUR 646.8
Description: Quantitative sandwich ELISA for measuring Mouse Autoimmune regulator (AIRE) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Aire ELISA Kit| Mouse Autoimmune regulator ELISA Kit
EF014266	Lifescience Market	96 Tests	EUR 826.8

Experimental Autoimmune Encephalomyelitis Complementary Peptide
5-01126	CHI Scientific	4 x 5mg	Ask for price

Experimental Autoimmune Encephalomyelitis Complementary Peptide
20-abx266248	Abbexa	EUR 560.40 EUR 910.80 EUR 410.40	10 mg 25 mg 5 mg

Regulator Kit
GAS1306	Scientific Laboratory Supplies	EACH	EUR 412.68

Energy Regulator
BAT1003	Scientific Laboratory Supplies	EACH	EUR 271.32

Eapa2 ELISA Kit| Mouse Experimental autoimmune prostatitis antig
EF013407	Lifescience Market	96 Tests	EUR 826.8

Glucokinase Regulator antibody
70R-31882	Fitzgerald	100 ug	EUR 392.4
Description: Rabbit polyclonal Glucokinase Regulator antibody

Glucokinase Regulator Antibody
33879-100ul	SAB	100ul	EUR 302.4

Glucokinase Regulator Antibody
33879-50ul	SAB	50ul	EUR 224.4

Glucokinase Regulator Antibody
ABD3277	Lifescience Market	100 ug	EUR 525.6

High Pressure Regulator
HPREG	Next Advance	1each	EUR 931.2
Description: High pressure regulator for use with PC77 pressure injection cells.

Mouse Eapa2/ Experimental autoimmune prostatitis antigen 2 ELISA Kit
E0435Mo	Sunlong	1 Kit	EUR 758.4

Mouse Eapa2(Experimental autoimmune prostatitis antigen 2) ELISA Kit
EM0797	FN Test	96T	EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Mus ;Sensitivity: 0.094 ng/ml

ELISA kit for Mouse Experimental autoimmune prostatitis antigen 2
EK4826	SAB	96 tests	EUR 804
Description: Enzyme-linked immunosorbent assay kit for quantification of Mouse Experimental autoimmune prostatitis antigen 2 in samples from serum, plasma, tissue homogenates and other biological fluids.

Rat Eapa2/ Experimental autoimmune prostatitis antigen 2 homolog ELISA Kit
E0313Ra	Sunlong	1 Kit	EUR 775.2

Glucokinase Regulator Blocking Peptide
DF3277-BP	Affbiotech	1mg	EUR 234

Glucokinase Regulator Conjugated Antibody
C33879	SAB	100ul	EUR 476.4

SLC2A4 Regulator (SLC2A4RG) Antibody
20-abx007254	Abbexa	EUR 493.20 EUR 710.40 EUR 376.80	100 ul 200 ul 50 ul

Glucokinase Regulator (GCKR) Antibody
20-abx013602	Abbexa	EUR 376.80 EUR 117.60 EUR 477.60 EUR 594.00	100 ug 10 ug 200 ug 300 µg

SLC2A4 Regulator (SLC2A4RG) Antibody
20-abx339963	Abbexa	EUR 493.20 EUR 360.00	100 ul 50 ul

Glucokinase Regulator (GCKR) Antibody
abx332634-100ul	Abbexa	100 ul	EUR 510

SLC2A4 Regulator (SLC2A4RG) Antibody
20-abx334405	Abbexa	EUR 493.20 EUR 2214.00 EUR 718.80 EUR 218.40 EUR 360.00	100 ug 1 mg 200 ug 20 ug 50 ug

Glucokinase Regulator (GCKR) Antibody
20-abx327833	Abbexa	EUR 376.80 EUR 292.80	100 ug 50 ug

Glucokinase Regulator (GCKR) Antibody
20-abx241527	Abbexa	EUR 493.20 EUR 360.00	100 ul 50 ul

Glucokinase Regulator (GCKR) Antibody
20-abx241821	Abbexa	EUR 493.20 EUR 360.00	100 ul 50 ul

SLC2A4 Regulator (SLC2A4RG) Antibody
20-abx213571	Abbexa	EUR 493.20 EUR 360.00	100 ul 50 ul

Glucokinase Regulator (GCKR) Antibody
20-abx213857	Abbexa	EUR 493.20 EUR 360.00	100 ul 50 ul

Glucokinase Regulator (GCKR) Antibody
20-abx214189	Abbexa	EUR 493.20 EUR 360.00	100 ul 50 ul

Recombinant human SLC2A4 regulator
P2685	FN Test	100ug	Ask for price
Description: Recombinant protein for human SLC2A4 regulator

Optional CO2 gas regulator
H2300-REG	Benchmark Scientific	1 PC	EUR 2895.76

Optional CO2 gas regulator
INC2312	Scientific Laboratory Supplies	EACH	EUR 409.26

In Line Pressure Regulator
INC6178	Scientific Laboratory Supplies	EACH	EUR 152.76

Jenway Propane Gas Regulator
FLA1028	Scientific Laboratory Supplies	EACH	EUR 298.68

Jenway Butane Gas Regulator
FLA1030	Scientific Laboratory Supplies	EACH	EUR 298.68

Jenway Natural Gas Regulator
FLA1032	Scientific Laboratory Supplies	EACH	EUR 87.78

Sherwood Regulator Natural Gas
FLA2016	Scientific Laboratory Supplies	EACH	EUR 292.98

Electronic Bunsen With Regulator
BA6101/C	Scientific Laboratory Supplies	EACH	EUR 660.06

PRESS REGULATOR W/GAUGE
ZFMQ000PR	Scientific Laboratory Supplies	EACH	EUR 298.68

GCKR Antibody / Glucokinase Regulator
RQ6555	NSJ Bioreagents	100ug	EUR 419
Description: The glucokinase regulatory protein (GKRP) also known as glucokinase (hexokinase 4) regulator (GCKR) is a protein produced in hepatocytes (liver cells). This gene encodes a protein belonging to the GCKR subfamily of the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme. This gene is considered a susceptibility gene candidate for a form of maturity-onset diabetes of the young (MODY).

Optional O2 gas regulator
H3565-O2REG	Benchmark Scientific	1 each	EUR 370.8

Human Transcriptional regulator ERG (ERG)
1-CSB-EP007781HUa2	Cusabio	EUR 456.00 EUR 256.80 EUR 1570.80 EUR 672.00 EUR 1047.60 EUR 314.40	100ug 10ug 1MG 200ug 500ug 50ug
Description: Recombinant Human Transcriptional regulator ERG(ERG) expressed in E.coli

Human Transcriptional regulator ERG (ERG)
1-CSB-YP007781HU	Cusabio	EUR 516.00 EUR 280.80 EUR 1809.60 EUR 770.40 EUR 1210.80 EUR 349.20	100ug 10ug 1MG 200ug 500ug 50ug
Description: Recombinant Human Transcriptional regulator ERG(ERG) expressed in Yeast

Recombinant E.Coli Ferric Uptake Regulator
7-05221	CHI Scientific	5µg	Ask for price

Recombinant E.Coli Ferric Uptake Regulator
7-05222	CHI Scientific	25µg	Ask for price

Recombinant E.Coli Ferric Uptake Regulator
7-05223	CHI Scientific	1mg	Ask for price

Active regulator of SIRT1 Antibody
20-abx109494	Abbexa	EUR 493.20 EUR 2214.00 EUR 718.80 EUR 218.40 EUR 360.00	100 ug 1 mg 200 ug 20 ug 50 ug

BCL2, Apoptosis Regulator (BCL2) Antibody
20-abx159344	Abbexa	EUR 326.40 EUR 276.00	100 ug 50 ug

Transcriptional Regulator Kaiso (ZBTB33) Antibody
20-abx147419	Abbexa	EUR 510.00 EUR 410.40	100 ug 50 ug

Transcriptional Regulator Kaiso (ZBTB33) Antibody
abx147439-100ug	Abbexa	100 ug	EUR 526.8

Transcriptional Regulator ERG (ERG) Antibody
20-abx125331	Abbexa	EUR 594.00 EUR 844.80 EUR 427.20	100 ul 200 ul 50 ul

Pleiotropic Regulator 1 (PLRG1) Antibody
20-abx135866	Abbexa	EUR 493.20 EUR 710.40 EUR 218.40 EUR 376.80	100 ul 200 ul 20 ul 50 ul

Transcriptional Regulator ERG (ERG) Antibody
20-abx141603	Abbexa	EUR 444.00 EUR 727.20 EUR 360.00	100 ul 200 ul 50 ul

Bifunctional Apoptosis Regulator (BAR) Antibody
20-abx142064	Abbexa	EUR 444.00 EUR 727.20 EUR 360.00	100 ul 200 ul 50 ul

Regulator Of Calcineurin 2 Antibody
20-abx115103	Abbexa	EUR 878.40 EUR 477.60	150 ul 50 ul

Retinitis Pigmentosa Gtpase Regulator Antibody
20-abx115144	Abbexa	EUR 878.40 EUR 477.60	150 ul 50 ul

Transcriptional Regulator ERG (ERG) Antibody
20-abx116611	Abbexa	EUR 878.40 EUR 477.60	150 ul 50 ul

MIER1 Transcriptional Regulator (Mier1) Antibody
20-abx113687	Abbexa	EUR 878.40 EUR 477.60	150 ul 50 ul

Bifunctional Apoptosis Regulator (BFAR) Antibody
20-abx006121	Abbexa	EUR 493.20 EUR 710.40 EUR 218.40 EUR 376.80	100 ul 200 ul 20 ul 50 ul

Transcriptional Regulator ERG (ERG) Antibody
20-abx001152	Abbexa	EUR 493.20 EUR 710.40 EUR 218.40 EUR 376.80	100 ul 200 ul 20 ul 50 ul

SLC9A3 Regulator 2 (SLC9A3R2) Antibody
20-abx014621	Abbexa	EUR 376.80 EUR 117.60 EUR 477.60 EUR 594.00	100 ug 10 ug 200 ug 300 µg

Transcriptional Regulator ATRX (ATRX) Antibody
20-abx013496	Abbexa	EUR 376.80 EUR 117.60 EUR 477.60 EUR 594.00	100 ug 10 ug 200 ug 300 µg

Bifunctional Apoptosis Regulator (BFAR) Antibody
abx029013-400ul	Abbexa	400 ul	EUR 627.6

Basic Protocol 1: Seeding enteroid fragments onto Transwells for monolayer formation Alternate Protocol: Seeding enteroid fragments for monolayer formation utilizing trituration Basic Protocol 2: Isolation of monocytes and derivation of immune cells from human peripheral blood Basic Protocol 3: Isolation of neutrophils from human peripheral blood Basic Protocol 4: Assembly of enteroid/macrophage or enteroid/neutrophil co-culture.