Mycobacterium smegmatis Bacteria Expressing Mycobacterium tuberculosis-Specific Rv1954A Induce Macrophage Activation and Modulate the Immune Response

Mycobacterium tuberculosis (M. tb), the intracellular pathogen inflicting tuberculosis, has developed mechanisms that endow infectivity and permit it to modulate host immune response for its survival. Genomic and proteomic analyses of non-pathogenic and pathogenic mycobacteria confirmed presence of genes and proteins which can be particular to M. tbIn silico research predicted that M.tb Rv1954A is a hypothetical secretory protein that reveals intrinsically disordered areas and possess B cell/T cell epitopes.

Treatment of macrophages with Rv1954A led to TLR4-mediated activation with concomitant improve in secretion of pro-inflammatory cytokines, IL-12 and TNF-α. In vitro research confirmed that rRv1954A protein or Rv1954A knock-in M. smegmatis (Ms_Rv1954A) prompts macrophages by enhancing the expression of CD80 and CD86.

An upregulation in the expression of CD40 and MHC I/II was famous in the presence of Rv1954A, pointing to its function in enhancing the affiliation of APCs with T cells and in the modulation of antigen presentation, respectively. Ms_Rv1954A confirmed elevated infectivity, induction of ROS and RNS, and apoptosis in RAW264.7 macrophage cells. Rv1954A imparted safety in opposition to oxidative and nitrosative stress, thereby enhancing the survival of Ms_Rv1954A inside macrophages.

Mice immunized with Ms_Rv1954A confirmed that splenomegaly and primed splenocytes restimulated with Rv1954A elicited a Th1 response. Infection of Ms_Rv1954A in mice by intratracheal instillation results in enhanced infiltration of lymphocytes in the lungs with out formation of granuloma. While Rv1954A is immunogenic, it didn’t trigger hostile pathology. Purified Rv1954A or Rv1954A knock-in M.

smegmatis (Ms_Rv1954A) elicited an almost two-fold increased titer of IgG response in mice, and PTB sufferers possess the next IgG titer in opposition to Rv1954A, additionally pointing to its utility as a diagnostic marker for TB. The noticed modulation of innate and adaptive immunity renders Rv1954A an important protein in the pathophysiology of this pathogen.

Cancer-Associated Fibroblasts-Derived Exosomes Suppress Immune Cell Function in Breast Cancer by way of the miR-92/PD-L1 Pathway

Cancer-associated fibroblasts (CAFs) are a vital part in the tumor microenvironment and have been reported to contribute to tumor development by many mechanisms; nevertheless, the detailed mechanism underlying the immune-suppression impact of CAFs shouldn’t be clearly outlined.

In this examine, human breast cancer-derived CAFs had been cultured, and CAF-derived exosomes in a tradition medium had been remoted. Using a miRNA profiles assay, we establish a considerably increased degree of microRNA-92 remoted in CAFs exosomes. After remedy by CAF-derived exosomes, breast most cancers cells specific increased programmed cell demise receptor ligand 1 (PD-L1), accompanied with elevated miR-92 expression.

Increased PD-L1 expression, which was induced by CAF-derived exosomes, considerably promotes apoptosis and impaired proliferation of T cells. The underlying mechanism of this impact was studied, proliferation and migration of breast most cancers cells had been elevated after the transfection of miR-92, LATS2 was acknowledged as a goal gene of miR-92, and additional confirmed by a luciferase assay.

Immunoprecipitation confirmed that LATS2 can work together with YAP1, chromatin immunoprecipitation confirmed that after nuclear translocation YAP1 might bind to the enhancer area of PD-L1 to promotes transcription exercise. Furthermore, the animal examine confirmed that CAFs considerably promoted tumor development and impaired the operate of tumor-infiltrated immune cells in vivo. Our information revealed a novel mechanism that may induce immune suppression in the tumor microenvironment.

Crossing boundaries: Interplay between the immune system and oligodendrocyte lineage cells

Oligodendrocytes and their progenitors are glial cells in the central nervous system, which have been primarily implicated with the homeostatic roles of axonal myelin ensheathment however function targets of the peripheral immune system assault in the context of ailments like a number of sclerosis.

This view of oligodendroglia as passive bystanders with no immunological properties was first challenged in the 1980s when it was reported that the cytokine interferon γ might induce the gene expression of the main histocompatibility complexes (MHC) class I and II. While the physiological function of this induction was controversial for many years to observe, current research counsel that oligodendroglia survey their setting, reply to a bigger array of cues and can certainly exert immunomodulatory features, that are notably related in the context of neurodegeneration and demyelinating ailments.

The various performance of oligodendroglia not solely regulates immune cell responses, but additionally hinders remyelination, and would possibly thereby be key to understanding MS illness pathology and selling regeneration after immune-mediated demyelination.

[Two serial events of delayed hemolytic transfusion reactions due to different primary immune response-induced irregular antibodies]

A 74-year-old lady with a historical past of pregnancies, however with out earlier transfusions, obtained a purple blood cell transfusion for aplstic anemia. She misplaced consciousness on account of extreme anemia two weeks later and was transported by ambulance to our hospital. Delayed hemolytic transfusion response (DHTR) was recognized based mostly on the detection of anti-E antibody and optimistic E antigen of the beforehand transfused product.

A transfusion of E antigen-negative purple cell merchandise was carried out. However, DHTR on account of anti-c antibody developed 16 d after the transfusion of a c antigen-positive product. Based on the onset of ≥14 d after the transfusions and the detection of a causative IgM-type antibody, DHTR on account of a major immune response was recognized. Because the incidence of DHTR is low, physicians hardly ever expertise it in scientific follow.

Pig Autoimmune Regulator ELISA kit

E07A0527-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Porcine Autoimmune Regulator in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Autoimmune Regulator ELISA kit

E04A0527-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Rabbit Autoimmune Regulator in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Autoimmune Regulator ELISA kit

E04A0527-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Rabbit Autoimmune Regulator in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Autoimmune Regulator ELISA kit

E04A0527-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Rabbit Autoimmune Regulator in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Autoimmune Regulator ELISA kit

E06A0527-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Goat Autoimmune Regulator in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Autoimmune Regulator ELISA kit

E06A0527-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Goat Autoimmune Regulator in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Autoimmune Regulator ELISA kit

E06A0527-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Goat Autoimmune Regulator in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Autoimmune Regulator ELISA kit

E09A0527-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Monkey Autoimmune Regulator in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Autoimmune Regulator ELISA kit

E09A0527-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Monkey Autoimmune Regulator in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Autoimmune Regulator ELISA kit

E09A0527-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Monkey Autoimmune Regulator in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Autoimmune Regulator ELISA kit

E08A0527-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Canine Autoimmune Regulator in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Autoimmune Regulator ELISA kit

E08A0527-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Canine Autoimmune Regulator in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Autoimmune Regulator ELISA kit

E08A0527-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Canine Autoimmune Regulator in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Autoimmune Regulator ELISA kit

E03A0527-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Mouse Autoimmune Regulator in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Autoimmune Regulator ELISA kit

E03A0527-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Mouse Autoimmune Regulator in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Autoimmune Regulator ELISA kit

E03A0527-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Mouse Autoimmune Regulator in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human AIRE/ Autoimmune regulator ELISA Kit

E0100Hu 1 Kit
EUR 726

Human Autoimmune Regulator (AIRE) ELISA Kit

DLR-AIRE-Hu-48T 48T
EUR 620.4
Description: A sandwich quantitative ELISA assay kit for detection of Human Autoimmune Regulator (AIRE) in samples from tissue homogenates or other biological fluids.

Human Autoimmune Regulator (AIRE) ELISA Kit

DLR-AIRE-Hu-96T 96T
EUR 807.6
Description: A sandwich quantitative ELISA assay kit for detection of Human Autoimmune Regulator (AIRE) in samples from tissue homogenates or other biological fluids.

ELISA kit for Human Autoimmune regulator

EK3200 96 tests
EUR 663.6
Description: Enzyme-linked immunosorbent assay kit for quantification of Human Autoimmune regulator in samples from serum, plasma, tissue homogenates and other biological fluids.

Human Autoimmune Regulator (AIRE) ELISA Kit

20-abx150773
  • EUR 8853.60
  • EUR 4719.60
  • EUR 1093.20
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human Autoimmune Regulator (AIRE) ELISA Kit

abx570732-96tests 96 tests
EUR 848.4

Human Autoimmune Regulator (AIRE) ELISA Kit

abx250784-96tests 96 tests
EUR 848.4

Human AIRE(Autoimmune regulator) ELISA Kit

EH1501 96T
EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml

Human Autoimmune regulator, AIRE ELISA KIT

ELI-12083h 96 Tests
EUR 988.8

Human Autoimmune Regulator (AIRE) ELISA Kit

RDR-AIRE-Hu-48Tests 48 Tests
EUR 652.8

Human Autoimmune Regulator (AIRE) ELISA Kit

RDR-AIRE-Hu-96Tests 96 Tests
EUR 907.2

Human Autoimmune Regulator(AIRE)ELISA Kit

QY-E00071 96T
EUR 433.2

Human Autoimmune Regulator (AIRE) ELISA Kit

RD-AIRE-Hu-48Tests 48 Tests
EUR 625.2

Human Autoimmune Regulator (AIRE) ELISA Kit

RD-AIRE-Hu-96Tests 96 Tests
EUR 867.6

Human Autoimmune Regulator (AIRE) ELISA Kit

SEC322Hu-10x96wellstestplate 10x96-wells test plate
EUR 5677.8
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Autoimmune Regulator (AIRE) in Tissue homogenates and other biological fluids.

Human Autoimmune Regulator (AIRE) ELISA Kit

SEC322Hu-1x48wellstestplate 1x48-wells test plate
EUR 572.76
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Autoimmune Regulator (AIRE) in Tissue homogenates and other biological fluids.

Human Autoimmune Regulator (AIRE) ELISA Kit

SEC322Hu-1x96wellstestplate 1x96-wells test plate
EUR 766.8
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Autoimmune Regulator (AIRE) in Tissue homogenates and other biological fluids.

Human Autoimmune Regulator (AIRE) ELISA Kit

SEC322Hu-5x96wellstestplate 5x96-wells test plate
EUR 3090.6
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Autoimmune Regulator (AIRE) in Tissue homogenates and other biological fluids.

Human Autoimmune Regulator (AIRE) ELISA Kit

4-SEC322Hu
  • EUR 5738.40
  • EUR 3031.20
  • EUR 768.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Autoimmune Regulator (AIRE) in samples from Tissue homogenates and other biological fluids. with no significant corss-reactivity with analogues from other species.

Autoimmune regulator Antibody

48041-100ul 100ul
EUR 399.6

Autoimmune regulator Antibody

48041-50ul 50ul
EUR 286.8

ELISA kit for Human AIRE (Autoimmune Regulator)

E-EL-H0536 1 plate of 96 wells
EUR 640.8
Description: A sandwich ELISA kit for quantitative measurement of Human AIRE (Autoimmune Regulator) in samples from Serum, Plasma, Cell supernatant

ELISA kit for Human AIRE (Autoimmune Regulator)

ELK3194 1 plate of 96 wells
EUR 518.4
Description: A sandwich ELISA kit for detection of Autoimmune Regulator from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

ELISA kit for Human Autoimmune regulator (AIRE)

KTE60636-48T 48T
EUR 398.4
Description: Quantitative sandwich ELISA for measuring Human Autoimmune regulator (AIRE) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human Autoimmune regulator (AIRE)

KTE60636-5platesof96wells 5 plates of 96 wells
EUR 2538
Description: Quantitative sandwich ELISA for measuring Human Autoimmune regulator (AIRE) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human Autoimmune regulator (AIRE)

KTE60636-96T 96T
EUR 646.8
Description: Quantitative sandwich ELISA for measuring Human Autoimmune regulator (AIRE) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Mouse Autoimmune Regulator (AIRE) ELISA Kit

DLR-AIRE-Mu-48T 48T
EUR 632.4
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Autoimmune Regulator (AIRE) in samples from tissue homogenates or other biological fluids.

Mouse Autoimmune Regulator (AIRE) ELISA Kit

DLR-AIRE-Mu-96T 96T
EUR 825.6
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Autoimmune Regulator (AIRE) in samples from tissue homogenates or other biological fluids.

Guinea pig Autoimmune Regulator ELISA kit

E05A0527-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Guinea pig Autoimmune Regulator in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig Autoimmune Regulator ELISA kit

E05A0527-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Guinea pig Autoimmune Regulator in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig Autoimmune Regulator ELISA kit

E05A0527-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Guinea pig Autoimmune Regulator in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Autoimmune Regulator (AIRE) ELISA Kit

20-abx153694
  • EUR 8853.60
  • EUR 4719.60
  • EUR 1093.20
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Chicken Autoimmune Regulator (AIRE) ELISA Kit

abx355828-96tests 96 tests
EUR 990

Rabbit Autoimmune Regulator (AIRE) ELISA Kit

abx363707-96tests 96 tests
EUR 990

Monkey Autoimmune Regulator (AIRE) ELISA Kit

abx359019-96tests 96 tests
EUR 990

Pig Autoimmune Regulator (AIRE) ELISA Kit

abx360670-96tests 96 tests
EUR 990

Mouse Autoimmune Regulator (AIRE) ELISA Kit

abx570926-96tests 96 tests
EUR 886.8

Mouse Autoimmune regulator, Aire ELISA KIT

ELI-11972m 96 Tests
EUR 1038

Mouse Autoimmune Regulator (AIRE) ELISA Kit

RDR-AIRE-Mu-48Tests 48 Tests
EUR 668.4

Mouse Autoimmune Regulator (AIRE) ELISA Kit

RDR-AIRE-Mu-96Tests 96 Tests
EUR 928.8

Mouse Autoimmune Regulator (AIRE) ELISA Kit

RD-AIRE-Mu-48Tests 48 Tests
EUR 639.6

Mouse Autoimmune Regulator (AIRE) ELISA Kit

RD-AIRE-Mu-96Tests 96 Tests
EUR 888

Mouse Autoimmune Regulator (AIRE) ELISA Kit

SEC322Mu-10x96wellstestplate 10x96-wells test plate
EUR 5834.88
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Autoimmune Regulator (AIRE) in Tissue homogenates and other biological fluids.

Mouse Autoimmune Regulator (AIRE) ELISA Kit

SEC322Mu-1x48wellstestplate 1x48-wells test plate
EUR 585.7
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Autoimmune Regulator (AIRE) in Tissue homogenates and other biological fluids.

Mouse Autoimmune Regulator (AIRE) ELISA Kit

SEC322Mu-1x96wellstestplate 1x96-wells test plate
EUR 785.28
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Autoimmune Regulator (AIRE) in Tissue homogenates and other biological fluids.

Mouse Autoimmune Regulator (AIRE) ELISA Kit

SEC322Mu-5x96wellstestplate 5x96-wells test plate
EUR 3173.76
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Autoimmune Regulator (AIRE) in Tissue homogenates and other biological fluids.

Mouse Autoimmune Regulator (AIRE) ELISA Kit

4-SEC322Mu
  • EUR 5895.60
  • EUR 3114.00
  • EUR 786.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Mouse Autoimmune Regulator (AIRE) in samples from Tissue homogenates and other biological fluids. with no significant corss-reactivity with analogues from other species.

Human Autoimmune Regulator (AIRE) CLIA Kit

abx196471-96tests 96 tests
EUR 990

Human Autoimmune Regulator (AIRE) CLIA Kit

20-abx493615
  • EUR 9567.60
  • EUR 5095.20
  • EUR 1177.20
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human Autoimmune Regulator (AIRE) Protein

20-abx652629
  • EUR 693.60
  • EUR 309.60
  • EUR 2064.00
  • EUR 828.00
  • EUR 510.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Autoimmune regulator (AIRE) Antibody

48129-100ul 100ul
EUR 399.6

Autoimmune regulator (AIRE) Antibody

48129-50ul 50ul
EUR 286.8

Autoimmune regulator (AIRE) Antibody

48149-100ul 100ul
EUR 399.6

Autoimmune regulator (AIRE) Antibody

48149-50ul 50ul
EUR 286.8

Autoimmune Regulator (AIRE) Antibody

20-abx171376
  • EUR 1028.40
  • EUR 526.80
  • 1 mg
  • 200 ug

Autoimmune Regulator (AIRE) Antibody

20-abx175527
  • EUR 1446.00
  • EUR 693.60
  • 1 mg
  • 200 ug

Autoimmune Regulator (AIRE) Antibody

20-abx175528
  • EUR 1479.60
  • EUR 710.40
  • 1 mg
  • 200 ug

Autoimmune Regulator (AIRE) Antibody

20-abx175529
  • EUR 1479.60
  • EUR 710.40
  • 1 mg
  • 200 ug

Autoimmune Regulator (AIRE) Antibody

abx117155-100ug 100 ug
EUR 560.4

Autoimmune Regulator (AIRE) Antibody

20-abx007582
  • EUR 360.00
  • EUR 526.80
  • EUR 226.80
  • 100 ul
  • 200 ul
  • 30 ul

Autoimmune Regulator (AIRE) Antibody

20-abx001466
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Autoimmune Regulator (AIRE) Antibody

abx019018-100ug 100 ug
EUR 410.4

Autoimmune Regulator (AIRE) Antibody

20-abx013298
  • EUR 376.80
  • EUR 117.60
  • EUR 477.60
  • EUR 594.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

Autoimmune Regulator (AIRE) Antibody

abx038141-100ug 100 ug
EUR 469.2

Autoimmune Regulator (AIRE) Antibody

abx230241-100ug 100 ug
EUR 577.2

Autoimmune Regulator (AIRE) Antibody

abx331461-100ul 100 ul
EUR 510

Autoimmune Regulator (AIRE) Antibody

20-abx312575
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Autoimmune Regulator (AIRE) Antibody

20-abx323992
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

Autoimmune Regulator (AIRE) Antibody

20-abx325675
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

Aire ELISA Kit| Mouse Autoimmune regulator ELISA Kit

EF014266 96 Tests
EUR 826.8

ELISA kit for Mouse AIRE (Autoimmune Regulator)

ELK6262 1 plate of 96 wells
EUR 518.4
Description: A sandwich ELISA kit for detection of Autoimmune Regulator from Mouse in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

Guinea pig Autoimmune Regulator (AIRE) ELISA Kit

abx358142-96tests 96 tests
EUR 990

ELISA kit for Mouse Autoimmune regulator (AIRE)

KTE70434-48T 48T
EUR 398.4
Description: Quantitative sandwich ELISA for measuring Mouse Autoimmune regulator (AIRE) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Mouse Autoimmune regulator (AIRE)

KTE70434-5platesof96wells 5 plates of 96 wells
EUR 2538
Description: Quantitative sandwich ELISA for measuring Mouse Autoimmune regulator (AIRE) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Mouse Autoimmune regulator (AIRE)

KTE70434-96T 96T
EUR 646.8
Description: Quantitative sandwich ELISA for measuring Mouse Autoimmune regulator (AIRE) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

CLIA kit for Human AIRE (Autoimmune Regulator)

E-CL-H0428 1 plate of 96 wells
EUR 700.8
Description: A sandwich CLIA kit for quantitative measurement of Human AIRE (Autoimmune Regulator) in samples from Serum, Plasma, Cell supernatant

Mouse Autoimmune Regulator (AIRE) CLIA Kit

20-abx493616
  • EUR 9567.60
  • EUR 5095.20
  • EUR 1177.20
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Autoimmune regulator (AIRE) Conjugated Antibody

C48129 100ul
EUR 476.4

Mouse Autoimmune Regulator (AIRE) Protein

20-abx652630
  • EUR 693.60
  • EUR 309.60
  • EUR 2064.00
  • EUR 828.00
  • EUR 510.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Mouse Autoimmune Regulator (AIRE) Protein

20-abx652631
  • EUR 693.60
  • EUR 309.60
  • EUR 2064.00
  • EUR 828.00
  • EUR 510.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Autoimmune Regulator (AIRE) Antibody (HRP)

20-abx312576
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Autoimmune Regulator (AIRE) Antibody (FITC)

20-abx312577
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Autoimmune Regulator (AIRE) Antibody (Biotin)

20-abx312578
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Autoimmune Regulator Phospho-Ser156 (AIRE pS156) Antibody

20-abx012667
  • EUR 376.80
  • EUR 117.60
  • EUR 477.60
  • EUR 594.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

Autoimmune Regulator Phospho-Ser156 (AIRE pS156) Antibody

20-abx323993
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

Custom Antibody titration by ELISA up to 2 rabbits and 1 bleed

ELISA-1 1
EUR 242.4

Eapa2 ELISA Kit| Mouse Experimental autoimmune prostatitis antig

EF013407 96 Tests
EUR 826.8

Frit Kit

FRIT-KIT 1each
EUR 148.8
Description: Kit to create frits in capillaries. Includes formamide, Kasil-1, Kasil-1624 and a cleaving tool.

Human Apoptosis regulator BAX ELISA kit

E01A1782-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Human Apoptosis regulator BAX in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Apoptosis regulator BAX ELISA kit

E01A1782-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Human Apoptosis regulator BAX in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Apoptosis regulator BAX ELISA kit

E01A1782-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Human Apoptosis regulator BAX in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Apoptosis regulator BAX ELISA Kit

CSB-E09344h-24T 1 plate of 24 wells
EUR 198
Description: Quantitativesandwich ELISA kit for measuring Human Apoptosis regulator BAX in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Human Apoptosis regulator BAX ELISA Kit

1-CSB-E09344h
  • EUR 843.60
  • EUR 5811.60
  • EUR 3084.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Human Apoptosis regulator BAX in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Human SLC2A4 regulator, SLC2A4RG ELISA KIT

ELI-18373h 96 Tests
EUR 988.8

Column Packing Kit

PACK-KIT 1pack
EUR 1242
Description: Column packing kit for pressure cells. Includes: HPREG regulator, TBNG10 tubing, CAP-75 capillary, and STRB5X2 stir bar.

Regulator Kit

GAS1306 EACH
EUR 412.68

PCR Mycoplasma Detection Kit

M034-Kit Kit
EUR 319.2

Mouse Eapa2/ Experimental autoimmune prostatitis antigen 2 ELISA Kit

E0435Mo 1 Kit
EUR 758.4

Mouse Eapa2(Experimental autoimmune prostatitis antigen 2) ELISA Kit

EM0797 96T
EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Mus ;Sensitivity: 0.094 ng/ml

ELISA kit for Mouse Experimental autoimmune prostatitis antigen 2

EK4826 96 tests
EUR 804
Description: Enzyme-linked immunosorbent assay kit for quantification of Mouse Experimental autoimmune prostatitis antigen 2 in samples from serum, plasma, tissue homogenates and other biological fluids.

Glucokinase Regulator Cell ELISA Kit

abx595841-96tests 96 tests
EUR 764.4

Human Bifunctional apoptosis regulator(BFAR) ELISA kit

E01B0794-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Human Bifunctional apoptosis regulator(BFAR) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Bifunctional apoptosis regulator(BFAR) ELISA kit

E01B0794-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Human Bifunctional apoptosis regulator(BFAR) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Bifunctional apoptosis regulator(BFAR) ELISA kit

E01B0794-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Human Bifunctional apoptosis regulator(BFAR) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Transcriptional regulator ERG(ERG) ELISA kit

E01T0612-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Human Transcriptional regulator ERG(ERG) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Transcriptional regulator ERG(ERG) ELISA kit

E01T0612-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Human Transcriptional regulator ERG(ERG) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Transcriptional regulator ERG(ERG) ELISA kit

E01T0612-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Human Transcriptional regulator ERG(ERG) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human BAX/ Apoptosis regulator BAX ELISA Kit

E0254Hu 1 Kit
EUR 675.6

Human ERG(Transcriptional regulator ERG) ELISA Kit

EH4920 96T
EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml

Human Bifunctional Apoptosis Regulator (BFAR) ELISA Kit

20-abx156882
  • EUR 8853.60
  • EUR 4719.60
  • EUR 1093.20
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human Interferon Production Regulator (IFNR) ELISA Kit

abx050082-96tests 96 tests
EUR 745.2

Human MIER1 Transcriptional Regulator (MIER1) ELISA Kit

abx381449-96tests 96 tests
EUR 1093.2

Human Pleiotropic Regulator 1 (PLRG1) ELISA Kit

abx382300-96tests 96 tests
EUR 1093.2

Human Bifunctional Apoptosis Regulator (BFAR) ELISA Kit

abx384630-96tests 96 tests
EUR 1093.2

Human Lysosomal Trafficking Regulator (LYST) ELISA Kit

abx385111-96tests 96 tests
EUR 1093.2

Human Transcriptional regulator Kaiso (ZBTB33) ELISA Kit

abx385521-96tests 96 tests
EUR 1093.2

Human Transcriptional Regulator ERG (ERG) ELISA Kit

abx387181-96tests 96 tests
EUR 1093.2

Human BAX(Apoptosis regulator BAX) ELISA Kit

EH0669 96T
EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.469 ng/ml

Human Pleiotropic regulator 1, PLRG1 ELISA KIT

ELI-38038h 96 Tests
EUR 988.8

Human Bifunctional apoptosis regulator, BFAR ELISA KIT

ELI-34714h 96 Tests
EUR 988.8

Human Lysosomal- trafficking regulator, LYST ELISA KIT

ELI-48080h 96 Tests
EUR 988.8

Human Apoptosis regulator BAX, BAX ELISA KIT

ELI-04433h 96 Tests
EUR 988.8

Human Transcriptional regulator ATRX, ATRX ELISA KIT

ELI-25220h 96 Tests
EUR 988.8

Human Transcriptional regulator Kaiso, ZBTB33 ELISA KIT

ELI-08145h 96 Tests
EUR 988.8

Human Transcriptional regulator ERG, ERG ELISA KIT

ELI-10025h 96 Tests
EUR 988.8

Human Pleiotropic Regulator 1(PLRG1)ELISA Kit

QY-E03727 96T
EUR 480

Human Bifunctional Apoptosis Regulator (BFAR) ELISA Kit

SEJ556Hu-10x96wellstestplate 10x96-wells test plate
EUR 5677.8
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Bifunctional Apoptosis Regulator (BFAR) in Tissue homogenates, cell lysates and other biological fluids.

Human Bifunctional Apoptosis Regulator (BFAR) ELISA Kit

SEJ556Hu-1x48wellstestplate 1x48-wells test plate
EUR 572.76
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Bifunctional Apoptosis Regulator (BFAR) in Tissue homogenates, cell lysates and other biological fluids.

Human Bifunctional Apoptosis Regulator (BFAR) ELISA Kit

SEJ556Hu-1x96wellstestplate 1x96-wells test plate
EUR 766.8
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Bifunctional Apoptosis Regulator (BFAR) in Tissue homogenates, cell lysates and other biological fluids.

Human Bifunctional Apoptosis Regulator (BFAR) ELISA Kit

SEJ556Hu-5x96wellstestplate 5x96-wells test plate
EUR 3090.6
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Bifunctional Apoptosis Regulator (BFAR) in Tissue homogenates, cell lysates and other biological fluids.

Human Bifunctional Apoptosis Regulator (BFAR) ELISA Kit

4-SEJ556Hu
  • EUR 5738.40
  • EUR 3031.20
  • EUR 768.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Bifunctional Apoptosis Regulator (BFAR) in samples from Tissue homogenates, cell lysates and other biological fluids. with no significant corss-reactivity with analogues from other species.

Cas9 Protein and T7 gRNA SmartNuclease Synthesis Kit

CAS400A-KIT 1 kit (10 rxn)
EUR 1332

Pesticide Kit Containing All 10 Multi-Compound Mixes

SPXPR-KIT 1ML
EUR 1923.18

CMV-hspCas9-T2A-Puro SmartNuclease Lentivector Plasmid + LentiStarter Packaging Kit

CASLV100PA-KIT 1 Kit
EUR 1358.4

CMV-hspCas9-EF1-GFP SmartNuclease Lentivector Plasmid + LentiStarter Packaging Kit

CASLV105PA-KIT 1 Kit
EUR 1358.4

MSCV-hspCas9-T2A-Puro SmartNuclease Lentivector Plasmid + LentiStarter Packaging Kit

CASLV120PA-KIT 1 Kit
EUR 1358.4

MSCV-hspCas9-EF1-GFP SmartNuclease Lentivector Plasmid + LentiStarter Packaging Kit

CASLV125PA-KIT 1 Kit
EUR 1358.4

Rat Eapa2/ Experimental autoimmune prostatitis antigen 2 homolog ELISA Kit

E0313Ra 1 Kit
EUR 775.2

Experimental Autoimmune Encephalomyelitis Complementary Peptide

5-01126 4 x 5mg Ask for price

Experimental Autoimmune Encephalomyelitis Complementary Peptide

20-abx266248
  • EUR 560.40
  • EUR 910.80
  • EUR 410.40
  • 10 mg
  • 25 mg
  • 5 mg

Multiplex gRNA Kit + EF1-T7-hspCas9-H1-gRNA linearized SmartNuclease vector

CAS700A-KIT 10 rxn
EUR 1358.4

Multiplex gRNA Kit + CAG-T7-hspCas9-H1-gRNA linearized SmartNuclease vector

CAS720A-KIT 10 rxn
EUR 1358.4

Multiplex gRNA Kit + CMV-T7-hspCas9-H1-gRNA linearized SmartNuclease vector

CAS740A-KIT 10 rxn
EUR 1358.4

T7 gRNA SmartNuclease Synthesis Kit (includes CAS510A-1 & T7 IVT synthesis reagents)

CAS510A-KIT 1 Kit
EUR 966

Cas9 Nickase: CMV-hspCas9(D10A)-T2A-Puro SmartNickase Lentivector Plasmid + LentiStarter Packaging Kit

CASLV200PA-KIT 1 Kit
EUR 1358.4

Cas9 Nickase: CMV-hspCas9(D10A)-EF1-GFP SmartNickase Lentivector Plasmid + LentiStarter Packaging Kit

CASLV205PA-KIT 1 Kit
EUR 1358.4

Cas9 Nickase: MSCV-hspCas9(D10A)-T2A-Puro SmartNickase Lentivector Plasmid + LentiStarter Packaging Kit

CASLV220PA-KIT 1 Kit
EUR 1358.4

Cas9 Nickase: MSCV-hspCas9(D10A)-EF1-GFP SmartNickase Lentivector Plasmid + LentiStarter Packaging Kit

CASLV225PA-KIT 1 Kit
EUR 1358.4

Multiplex gRNA Kit + Cas9 Nickase: EF1-T7-hspCas9-nickase-H1-gRNA linearized SmartNickase vector

CAS750A-KIT 10 rxn
EUR 1358.4

Multiplex gRNA Kit + Cas9 Nickase: CAG-T7-hspCas9-nickase-H1-gRNA linearized SmartNickase vector

CAS770A-KIT 10 rxn
EUR 1358.4

However, in our case, DHTR on account of a major immune response, which is even rarer in DHTR circumstances, developed twice inside a brief interval. A historical past of transfusion and being pregnant in addition to preexisting irregular antibodies have been recognized as danger components for DHTR. Thus, extra consideration must be paid to the danger of DHTR redevelopment by repeated transfusions.

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