Mycobacterium smegmatis Bacteria Expressing Mycobacterium tuberculosis-Specific Rv1954A Induce Macrophage Activation and Modulate the Immune Response

Mycobacterium tuberculosis (M. tb), the intracellular pathogen inflicting tuberculosis, has developed mechanisms that endow infectivity and permit it to modulate host immune response for its survival. Genomic and proteomic analyses of non-pathogenic and pathogenic mycobacteria confirmed presence of genes and proteins which can be particular to M. tbIn silico research predicted that M.tb Rv1954A is a hypothetical secretory protein that reveals intrinsically disordered areas and possess B cell/T cell epitopes.

Treatment of macrophages with Rv1954A led to TLR4-mediated activation with concomitant improve in secretion of pro-inflammatory cytokines, IL-12 and TNF-α. In vitro research confirmed that rRv1954A protein or Rv1954A knock-in M. smegmatis (Ms_Rv1954A) prompts macrophages by enhancing the expression of CD80 and CD86.

An upregulation in the expression of CD40 and MHC I/II was famous in the presence of Rv1954A, pointing to its function in enhancing the affiliation of APCs with T cells and in the modulation of antigen presentation, respectively. Ms_Rv1954A confirmed elevated infectivity, induction of ROS and RNS, and apoptosis in RAW264.7 macrophage cells. Rv1954A imparted safety in opposition to oxidative and nitrosative stress, thereby enhancing the survival of Ms_Rv1954A inside macrophages.

Mice immunized with Ms_Rv1954A confirmed that splenomegaly and primed splenocytes restimulated with Rv1954A elicited a Th1 response. Infection of Ms_Rv1954A in mice by intratracheal instillation results in enhanced infiltration of lymphocytes in the lungs with out formation of granuloma. While Rv1954A is immunogenic, it didn’t trigger hostile pathology. Purified Rv1954A or Rv1954A knock-in M.

smegmatis (Ms_Rv1954A) elicited an almost two-fold increased titer of IgG response in mice, and PTB sufferers possess the next IgG titer in opposition to Rv1954A, additionally pointing to its utility as a diagnostic marker for TB. The noticed modulation of innate and adaptive immunity renders Rv1954A an important protein in the pathophysiology of this pathogen.

Cancer-Associated Fibroblasts-Derived Exosomes Suppress Immune Cell Function in Breast Cancer by way of the miR-92/PD-L1 Pathway

Cancer-associated fibroblasts (CAFs) are a vital part in the tumor microenvironment and have been reported to contribute to tumor development by many mechanisms; nevertheless, the detailed mechanism underlying the immune-suppression impact of CAFs shouldn’t be clearly outlined.

In this examine, human breast cancer-derived CAFs had been cultured, and CAF-derived exosomes in a tradition medium had been remoted. Using a miRNA profiles assay, we establish a considerably increased degree of microRNA-92 remoted in CAFs exosomes. After remedy by CAF-derived exosomes, breast most cancers cells specific increased programmed cell demise receptor ligand 1 (PD-L1), accompanied with elevated miR-92 expression.

Increased PD-L1 expression, which was induced by CAF-derived exosomes, considerably promotes apoptosis and impaired proliferation of T cells. The underlying mechanism of this impact was studied, proliferation and migration of breast most cancers cells had been elevated after the transfection of miR-92, LATS2 was acknowledged as a goal gene of miR-92, and additional confirmed by a luciferase assay.

Immunoprecipitation confirmed that LATS2 can work together with YAP1, chromatin immunoprecipitation confirmed that after nuclear translocation YAP1 might bind to the enhancer area of PD-L1 to promotes transcription exercise. Furthermore, the animal examine confirmed that CAFs considerably promoted tumor development and impaired the operate of tumor-infiltrated immune cells in vivo. Our information revealed a novel mechanism that may induce immune suppression in the tumor microenvironment.

Crossing boundaries: Interplay between the immune system and oligodendrocyte lineage cells

Oligodendrocytes and their progenitors are glial cells in the central nervous system, which have been primarily implicated with the homeostatic roles of axonal myelin ensheathment however function targets of the peripheral immune system assault in the context of ailments like a number of sclerosis.

This view of oligodendroglia as passive bystanders with no immunological properties was first challenged in the 1980s when it was reported that the cytokine interferon γ might induce the gene expression of the main histocompatibility complexes (MHC) class I and II. While the physiological function of this induction was controversial for many years to observe, current research counsel that oligodendroglia survey their setting, reply to a bigger array of cues and can certainly exert immunomodulatory features, that are notably related in the context of neurodegeneration and demyelinating ailments.

The various performance of oligodendroglia not solely regulates immune cell responses, but additionally hinders remyelination, and would possibly thereby be key to understanding MS illness pathology and selling regeneration after immune-mediated demyelination.

[Two serial events of delayed hemolytic transfusion reactions due to different primary immune response-induced irregular antibodies]

A 74-year-old lady with a historical past of pregnancies, however with out earlier transfusions, obtained a purple blood cell transfusion for aplstic anemia. She misplaced consciousness on account of extreme anemia two weeks later and was transported by ambulance to our hospital. Delayed hemolytic transfusion response (DHTR) was recognized based mostly on the detection of anti-E antibody and optimistic E antigen of the beforehand transfused product.

A transfusion of E antigen-negative purple cell merchandise was carried out. However, DHTR on account of anti-c antibody developed 16 d after the transfusion of a c antigen-positive product. Based on the onset of ≥14 d after the transfusions and the detection of a causative IgM-type antibody, DHTR on account of a major immune response was recognized. Because the incidence of DHTR is low, physicians hardly ever expertise it in scientific follow.

Human AIRE (Autoimmune Regulator) ELISA Kit

EKE60371-5x96T 5x96T
EUR 3124.08

Human AIRE (Autoimmune Regulator) ELISA Kit

EKE60371-96T 96T
EUR 657.7

Human AIRE(Autoimmune Regulator) ELISA Kit

ELK3194-48T 48T Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human AIRE. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human AIRE. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Human AIRE, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Human AIRE in the samples is then determined by comparing the OD of the samples to the standard curve.

Human AIRE(Autoimmune Regulator) ELISA Kit

ELK3194-96T 96T Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human AIRE. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human AIRE. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Human AIRE, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Human AIRE in the samples is then determined by comparing the OD of the samples to the standard curve.

Human Autoimmune Regulator (AIRE) ELISA Kit

20-abx150773
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  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human Autoimmune Regulator (AIRE) ELISA Kit

abx250784-96tests 96 tests
EUR 848.4

Human Autoimmune Regulator (AIRE) ELISA Kit

abx570732-96tests 96 tests
EUR 848.4

Human Autoimmune Regulator (AIRE) ELISA Kit

DLR-AIRE-Hu 96T
EUR 463
Description: tissue homogenates or other biological fluids.

Human Autoimmune Regulator (AIRE) ELISA Kit

DLR-AIRE-Hu-48T 48T
EUR 620.4
Description: A sandwich quantitative ELISA assay kit for detection of Human Autoimmune Regulator (AIRE) in samples from tissue homogenates or other biological fluids.

Human Autoimmune Regulator (AIRE) ELISA Kit

DLR-AIRE-Hu-96T 96T
EUR 807.6
Description: A sandwich quantitative ELISA assay kit for detection of Human Autoimmune Regulator (AIRE) in samples from tissue homogenates or other biological fluids.

Human Autoimmune Regulator (AIRE) ELISA Kit

EKN43760-48T 48T
EUR 378.7

Human Autoimmune Regulator (AIRE) ELISA Kit

EKN43760-5x96T 5x96T
EUR 2569.75

Human Autoimmune Regulator (AIRE) ELISA Kit

EKN43760-96T 96T
EUR 541

Human Autoimmune regulator, AIRE ELISA KIT

ELI-12083h 96 Tests
EUR 988.8

Human Autoimmune Regulator (AIRE) ELISA Kit

EKU02649-48T 48T
EUR 555.66

Human Autoimmune Regulator (AIRE) ELISA Kit

EKU02649-5x96T 5x96T
EUR 3770.55

Human Autoimmune Regulator (AIRE) ELISA Kit

EKU02649-96T 96T
EUR 793.8

Human Autoimmune Regulator (AIRE) ELISA Kit

DL-AIRE-Hu 96T
EUR 441
Description: tissue homogenates or other biological fluids.

Human Autoimmune regulator (AIRE) ELISA Kit

AE19265HU-48Tests 48 Tests
EUR 325
Description: Human (Homo sapiens)

Human Autoimmune regulator (AIRE) ELISA Kit

AE19265HU-96Tests 96 Tests
EUR 610
Description: Human (Homo sapiens)

Human Autoimmune regulator (AIRE) ELISA Kit

KTE60636-48T 48T
EUR 339
Description: This Human Autoimmune regulator (AIRE) ELISA Kit employs a two-site sandwich ELISA to quantitate AIRE.

Human Autoimmune regulator (AIRE) ELISA Kit

KTE60636-96T 96T
EUR 589
Description: This Human Autoimmune regulator (AIRE) ELISA Kit employs a two-site sandwich ELISA to quantitate AIRE.

Human Autoimmune regulator (AIRE) ELISA Kit

KTE60636-96T5 96 T×5
EUR 2629
Description: This Human Autoimmune regulator (AIRE) ELISA Kit employs a two-site sandwich ELISA to quantitate AIRE.

Human Autoimmune regulator (AIRE) ELISA Kit

KTE60636-96T50 96 T×50
EUR 24569
Description: This Human Autoimmune regulator (AIRE) ELISA Kit employs a two-site sandwich ELISA to quantitate AIRE.

Human Autoimmune regulator (AIRE) ELISA Kit

RK10235 96T
EUR 280

Human Autoimmune Regulator(AIRE)ELISA Kit

QY-E00071 96T
EUR 433.2

Human Autoimmune Regulator (AIRE) ELISA Kit

RD-AIRE-Hu-48T 48T
EUR 452.7
Description: tissue homogenates and other biological fluids.

Human Autoimmune Regulator (AIRE) ELISA Kit

RD-AIRE-Hu-48Tests 48 Tests
EUR 625.2

Human Autoimmune Regulator (AIRE) ELISA Kit

RD-AIRE-Hu-96T 96T
EUR 646.7
Description: tissue homogenates and other biological fluids.

Human Autoimmune Regulator (AIRE) ELISA Kit

RD-AIRE-Hu-96Tests 96 Tests
EUR 867.6

Human Autoimmune Regulator (AIRE) ELISA Kit

RDR-AIRE-Hu-48T 48T
EUR 475.34
Description: tissue homogenates and other biological fluids.

Human Autoimmune Regulator (AIRE) ELISA Kit

RDR-AIRE-Hu-48Tests 48 Tests
EUR 652.8

Human Autoimmune Regulator (AIRE) ELISA Kit

RDR-AIRE-Hu-96T 96T
EUR 679.04
Description: tissue homogenates and other biological fluids.

Human Autoimmune Regulator (AIRE) ELISA Kit

RDR-AIRE-Hu-96Tests 96 Tests
EUR 907.2

Human Autoimmune Regulator (AIRE) ELISA Kit

SEC322Hu-10x96wellstestplate 10x96-wells test plate
EUR 5677.8
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Autoimmune Regulator (AIRE) in Tissue homogenates and other biological fluids.

Human Autoimmune Regulator (AIRE) ELISA Kit

SEC322Hu-1x48wellstestplate 1x48-wells test plate
EUR 572.76
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Autoimmune Regulator (AIRE) in Tissue homogenates and other biological fluids.

Human Autoimmune Regulator (AIRE) ELISA Kit

SEC322Hu-1x96wellstestplate 1x96-wells test plate
EUR 766.8
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Autoimmune Regulator (AIRE) in Tissue homogenates and other biological fluids.

Human Autoimmune Regulator (AIRE) ELISA Kit

SEC322Hu-5x96wellstestplate 5x96-wells test plate
EUR 3090.6
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Autoimmune Regulator (AIRE) in Tissue homogenates and other biological fluids.

Human Autoimmune Regulator (AIRE) ELISA Kit

4-SEC322Hu
  • Ask for price
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  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Autoimmune Regulator (AIRE) in samples from Tissue homogenates and other biological fluids. with no significant corss-reactivity with analogues from other species.

Human Autoimmune regulator(AIRE)ELISA kit

YLA4398HU-48T 48T Ask for price

Human Autoimmune regulator(AIRE)ELISA kit

YLA4398HU-96T 96T Ask for price

Rat Autoimmune Regulator ELISA kit

E02A0527-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Rat Autoimmune Regulator in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Autoimmune Regulator ELISA kit

E02A0527-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Rat Autoimmune Regulator in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Autoimmune Regulator ELISA kit

E02A0527-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Rat Autoimmune Regulator in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Autoimmune Regulator ELISA kit

E01A8993 96T
EUR 700
Description: ELISA

Dog Autoimmune Regulator ELISA kit

E08A0527-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Canine Autoimmune Regulator in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Autoimmune Regulator ELISA kit

E08A0527-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Canine Autoimmune Regulator in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Autoimmune Regulator ELISA kit

E08A0527-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Canine Autoimmune Regulator in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Autoimmune Regulator ELISA kit

E07A0527-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Porcine Autoimmune Regulator in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Autoimmune Regulator ELISA kit

E07A0527-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Porcine Autoimmune Regulator in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Autoimmune Regulator ELISA kit

E07A0527-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Porcine Autoimmune Regulator in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Autoimmune Regulator ELISA kit

E01A43914 96T
EUR 700
Description: ELISA

Goat Autoimmune Regulator ELISA kit

E06A0527-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Goat Autoimmune Regulator in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Autoimmune Regulator ELISA kit

E06A0527-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Goat Autoimmune Regulator in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Autoimmune Regulator ELISA kit

E06A0527-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Goat Autoimmune Regulator in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Autoimmune Regulator ELISA kit

E01A17735 96T
EUR 700
Description: ELISA

Mouse Autoimmune Regulator ELISA kit

E03A0527-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Mouse Autoimmune Regulator in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Autoimmune Regulator ELISA kit

E03A0527-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Mouse Autoimmune Regulator in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Autoimmune Regulator ELISA kit

E03A0527-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Mouse Autoimmune Regulator in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Sheep Autoimmune Regulator ELISA kit

E01A96207 96T
EUR 700
Description: ELISA

Mouse Autoimmune Regulator ELISA Kit

IMSAIREKT each
EUR 752
Description: Mouse Autoimmune Regulator ELISA Kit

Canine Autoimmune Regulator ELISA kit

E01A61349 96T
EUR 700
Description: ELISA

Monkey Autoimmune Regulator ELISA kit

E01A70061 96T
EUR 700
Description: ELISA

Rabbit Autoimmune Regulator ELISA kit

E01A26482 96T
EUR 700
Description: ELISA

Rabbit Autoimmune Regulator ELISA kit

E04A0527-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Rabbit Autoimmune Regulator in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Autoimmune Regulator ELISA kit

E04A0527-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Rabbit Autoimmune Regulator in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Autoimmune Regulator ELISA kit

E04A0527-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Rabbit Autoimmune Regulator in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Bovine Autoimmune Regulator ELISA kit

E01A78778 96T
EUR 700
Description: ELISA

Monkey Autoimmune Regulator ELISA kit

E09A0527-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Monkey Autoimmune Regulator in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Autoimmune Regulator ELISA kit

E09A0527-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Monkey Autoimmune Regulator in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Autoimmune Regulator ELISA kit

E09A0527-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Monkey Autoimmune Regulator in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

ELISA kit for Human Autoimmune regulator (AIRE)

KTE60636-5platesof96wells 5 plates of 96 wells
EUR 2538
Description: Quantitative sandwich ELISA for measuring Human Autoimmune regulator (AIRE) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Porcine Autoimmune Regulator ELISA kit

E01A52631 96T
EUR 700
Description: ELISA

Chicken Autoimmune Regulator ELISA kit

E01A87504 96T
EUR 700
Description: ELISA

ELISA kit for Human AIRE (Autoimmune Regulator)

E-EL-H0536 1 plate of 96 wells
EUR 640.8
Description: A sandwich ELISA kit for quantitative measurement of Human AIRE (Autoimmune Regulator) in samples from Serum, Plasma, Cell supernatant

ELISA kit for Human AIRE (Autoimmune Regulator)

ELK3194 1 plate of 96 wells
EUR 518.4
Description: A sandwich ELISA kit for detection of Autoimmune Regulator from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

Guinea Pig Autoimmune Regulator ELISA kit

E01A35196 96T
EUR 700
Description: ELISA

Guinea pig Autoimmune Regulator ELISA kit

E05A0527-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Guinea pig Autoimmune Regulator in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig Autoimmune Regulator ELISA kit

E05A0527-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Guinea pig Autoimmune Regulator in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig Autoimmune Regulator ELISA kit

E05A0527-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Guinea pig Autoimmune Regulator in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse AIRE(Autoimmune Regulator) ELISA Kit

ELK6262-48T 48T Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse AIRE. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse AIRE. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Mouse AIRE, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Mouse AIRE in the samples is then determined by comparing the OD of the samples to the standard curve.

Mouse AIRE(Autoimmune Regulator) ELISA Kit

ELK6262-96T 96T Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse AIRE. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse AIRE. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Mouse AIRE, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Mouse AIRE in the samples is then determined by comparing the OD of the samples to the standard curve.

Pig Autoimmune Regulator (AIRE) ELISA Kit

abx360670-96tests 96 tests
EUR 990

Rat Autoimmune regulator(AIRE)ELISA kit

YLA1691RA-48T 48T Ask for price

Rat Autoimmune regulator(AIRE)ELISA kit

YLA1691RA-96T 96T Ask for price

Autoimmune Regulator (AIRE) Cell ELISA Kit

abx595022-100g 100 µg Ask for price

Autoimmune Regulator (AIRE) Cell ELISA Kit

abx595022-10g 10 µg
EUR 493.75

Autoimmune Regulator (AIRE) Cell ELISA Kit

abx595022-50g 50 µg Ask for price

Mouse Autoimmune Regulator (AIRE) ELISA Kit

abx570926-96tests 96 tests
EUR 886.8

Mouse Autoimmune Regulator (AIRE) ELISA Kit

20-abx153694
  • Ask for price
  • Ask for price
  • Ask for price
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Mouse Autoimmune Regulator (AIRE) ELISA Kit

DLR-AIRE-Mu 96T
EUR 475
Description: tissue homogenates or other biological fluids.

Mouse Autoimmune Regulator (AIRE) ELISA Kit

DLR-AIRE-Mu-48T 48T
EUR 632.4
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Autoimmune Regulator (AIRE) in samples from tissue homogenates or other biological fluids.

Mouse Autoimmune Regulator (AIRE) ELISA Kit

DLR-AIRE-Mu-96T 96T
EUR 825.6
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Autoimmune Regulator (AIRE) in samples from tissue homogenates or other biological fluids.

Mouse Autoimmune Regulator (AIRE) ELISA Kit

EKN43761-48T 48T
EUR 389.62

Mouse Autoimmune Regulator (AIRE) ELISA Kit

EKN43761-5x96T 5x96T
EUR 2643.85

Mouse Autoimmune Regulator (AIRE) ELISA Kit

EKN43761-96T 96T
EUR 556.6

Mouse Autoimmune regulator (AIRE) ELISA Kit

EK7318 96Т
EUR 799

Mouse Autoimmune regulator, Aire ELISA KIT

ELI-11972m 96 Tests
EUR 1038

Mouse Autoimmune Regulator (AIRE) ELISA Kit

EKU02650-48T 48T
EUR 571.55

Mouse Autoimmune Regulator (AIRE) ELISA Kit

EKU02650-5x96T 5x96T
EUR 3878.38

Mouse Autoimmune Regulator (AIRE) ELISA Kit

EKU02650-96T 96T
EUR 816.5

Mouse Autoimmune Regulator (AIRE) ELISA Kit

DL-AIRE-Mu 96T
EUR 453
Description: tissue homogenates or other biological fluids.

Mouse Autoimmune regulator (AIRE) ELISA Kit

AE19266MO-48Tests 48 Tests
EUR 325
Description: Mouse (Mus musculus)

Mouse Autoimmune regulator (AIRE) ELISA Kit

AE19266MO-96Tests 96 Tests
EUR 610
Description: Mouse (Mus musculus)

Mouse Autoimmune regulator (AIRE) ELISA Kit

RK12608 96T
EUR 280

Mouse Autoimmune Regulator (AIRE) ELISA Kit

RD-AIRE-Mu-48T 48T
EUR 464.3
Description: tissue homogenates and other biological fluids.

Mouse Autoimmune Regulator (AIRE) ELISA Kit

RD-AIRE-Mu-48Tests 48 Tests
EUR 639.6

Mouse Autoimmune Regulator (AIRE) ELISA Kit

RD-AIRE-Mu-96T 96T
EUR 663.3
Description: tissue homogenates and other biological fluids.

Mouse Autoimmune Regulator (AIRE) ELISA Kit

RD-AIRE-Mu-96Tests 96 Tests
EUR 888

Mouse Autoimmune Regulator (AIRE) ELISA Kit

RDR-AIRE-Mu-48T 48T
EUR 487.52
Description: tissue homogenates and other biological fluids.

Mouse Autoimmune Regulator (AIRE) ELISA Kit

RDR-AIRE-Mu-48Tests 48 Tests
EUR 668.4

Mouse Autoimmune Regulator (AIRE) ELISA Kit

RDR-AIRE-Mu-96T 96T
EUR 696.47
Description: tissue homogenates and other biological fluids.

Mouse Autoimmune Regulator (AIRE) ELISA Kit

RDR-AIRE-Mu-96Tests 96 Tests
EUR 928.8

Mouse Autoimmune Regulator (AIRE) ELISA Kit

SEC322Mu-10x96wellstestplate 10x96-wells test plate
EUR 5834.88
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Autoimmune Regulator (AIRE) in Tissue homogenates and other biological fluids.

Mouse Autoimmune Regulator (AIRE) ELISA Kit

SEC322Mu-1x48wellstestplate 1x48-wells test plate
EUR 585.7
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Autoimmune Regulator (AIRE) in Tissue homogenates and other biological fluids.

Mouse Autoimmune Regulator (AIRE) ELISA Kit

SEC322Mu-1x96wellstestplate 1x96-wells test plate
EUR 785.28
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Autoimmune Regulator (AIRE) in Tissue homogenates and other biological fluids.

Mouse Autoimmune Regulator (AIRE) ELISA Kit

SEC322Mu-5x96wellstestplate 5x96-wells test plate
EUR 3173.76
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Autoimmune Regulator (AIRE) in Tissue homogenates and other biological fluids.

Mouse Autoimmune Regulator (AIRE) ELISA Kit

4-SEC322Mu
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  • Ask for price
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Mouse Autoimmune Regulator (AIRE) in samples from Tissue homogenates and other biological fluids. with no significant corss-reactivity with analogues from other species.

Autoimmune regulator

AP78947 1mg
EUR 2640

Autoimmune regulator

AP80605 1mg
EUR 2640

Rabbit Autoimmune Regulator (AIRE) ELISA Kit

abx363707-96tests 96 tests
EUR 990

Monkey Autoimmune Regulator (AIRE) ELISA Kit

abx359019-96tests 96 tests
EUR 990

Aire ELISA Kit| Mouse Autoimmune regulator ELISA Kit

EF014266 96 Tests
EUR 826.8

Chicken Autoimmune Regulator (AIRE) ELISA Kit

abx355828-96tests 96 tests
EUR 990

Human Autoimmune Regulator (AIRE) CLIA Kit

abx196471-96tests 96 tests
EUR 990

Human Autoimmune Regulator (AIRE) CLIA Kit

20-abx493615
  • Ask for price
  • Ask for price
  • Ask for price
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human Autoimmune Regulator (AIRE) CLIA Kit

abx196471-100l 100 µl Ask for price

Human Autoimmune Regulator (AIRE) CLIA Kit

abx196471-50l 50 µl
EUR 618.75

Human AIRE -Autoimmune Regulator- CLIA Kit

E-CL-H0428-24Tests 24 Tests
EUR 180
Description: Sandwich

Human AIRE -Autoimmune Regulator- CLIA Kit

E-CL-H0428-48Tests 48 Tests
EUR 546
Description: Sandwich

Human AIRE -Autoimmune Regulator- CLIA Kit

E-CL-H0428-96Tests 96 Tests
EUR 682
Description: Sandwich

Human AIRE -Autoimmune Regulator- CLIA Kit

E-CL-H0428-96Tests10 96 Tests *10
EUR 6820
Description: Sandwich

Human AIRE -Autoimmune Regulator- CLIA Kit

E-CL-H0428-96Tests5 96 Tests *5
EUR 3410
Description: Sandwich

ELISA kit for Mouse AIRE (Autoimmune Regulator)

ELK6262 1 plate of 96 wells
EUR 518.4
Description: A sandwich ELISA kit for detection of Autoimmune Regulator from Mouse in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

ELISA kit for Mouse Autoimmune regulator (AIRE)

KTE70434-48T 48T
EUR 398.4
Description: Quantitative sandwich ELISA for measuring Mouse Autoimmune regulator (AIRE) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Mouse Autoimmune regulator (AIRE)

KTE70434-5platesof96wells 5 plates of 96 wells
EUR 2538
Description: Quantitative sandwich ELISA for measuring Mouse Autoimmune regulator (AIRE) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Mouse Autoimmune regulator (AIRE)

KTE70434-96T 96T
EUR 646.8
Description: Quantitative sandwich ELISA for measuring Mouse Autoimmune regulator (AIRE) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Guinea pig Autoimmune Regulator (AIRE) ELISA Kit

abx358142-96tests 96 tests
EUR 990

Autoimmune regulator (AIRE)

E8R1107-1 100ul
EUR 275
Description: Available in various conjugation types.

Autoimmune regulator (AIRE)

E8R1305-5 100ul
EUR 275
Description: Available in various conjugation types.

CLIA kit for Human AIRE (Autoimmune Regulator)

E-CL-H0428 1 plate of 96 wells
EUR 700.8
Description: A sandwich CLIA kit for quantitative measurement of Human AIRE (Autoimmune Regulator) in samples from Serum, Plasma, Cell supernatant

Human Autoimmune Regulator (AIRE) Protein

20-abx652629
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  • Ask for price
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  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Human Autoimmune Regulator (AIRE) Protein

abx652629-100g 100 µg Ask for price

Human Autoimmune Regulator (AIRE) Protein

abx652629-10g 10 µg
EUR 1800

Human Autoimmune Regulator (AIRE) Protein

abx652629-50g 50 µg
EUR 4525

Autoimmune regulator Antibody

48041 100ul
EUR 429

Autoimmune regulator Antibody

48041-100ul 100ul
EUR 399.6

Autoimmune regulator Antibody

48041-50ul 50ul
EUR 286.8

Mouse Autoimmune Regulator (AIRE) CLIA Kit

20-abx493616
  • Ask for price
  • Ask for price
  • Ask for price
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human Autoimmune Regulator Chemiluminescent Immunoassay Kit

IHUAIREKTC each
EUR 545
Description: Human Autoimmune Regulator Chemiluminescent Immunoassay Kit

Autoimmune Regulator (AIRE) Antibody

abx117155-100ug 100 ug
EUR 560.4

Autoimmune Regulator (AIRE) Antibody

20-abx007582
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  • Ask for price
  • Ask for price
  • 100 ul
  • 200 ul
  • 30 ul

Autoimmune Regulator (AIRE) Antibody

abx038141-100ug 100 ug
EUR 469.2

Autoimmune Regulator (AIRE) Antibody

abx019018-100ug 100 ug
EUR 410.4

Autoimmune Regulator (AIRE) Antibody

20-abx013298
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

Autoimmune Regulator (AIRE) Antibody

20-abx001466
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  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Autoimmune regulator (AIRE) Antibody

48129 100ul
EUR 429

Autoimmune regulator (AIRE) Antibody

48129-100ul 100ul
EUR 399.6

Autoimmune regulator (AIRE) Antibody

48129-50ul 50ul
EUR 286.8

Autoimmune regulator (AIRE) Antibody

48149 100ul
EUR 429

Autoimmune regulator (AIRE) Antibody

48149-100ul 100ul
EUR 399.6

Autoimmune regulator (AIRE) Antibody

48149-50ul 50ul
EUR 286.8

Autoimmune Regulator (AIRE) Antibody

abx230241-100ug 100 ug
EUR 577.2

Autoimmune Regulator (AIRE) Antibody

20-abx171376
  • Ask for price
  • Ask for price
  • 1 mg
  • 200 ug

Autoimmune Regulator (AIRE) Antibody

20-abx175527
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  • Ask for price
  • 1 mg
  • 200 ug

Autoimmune Regulator (AIRE) Antibody

20-abx175528
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  • Ask for price
  • 1 mg
  • 200 ug

However, in our case, DHTR on account of a major immune response, which is even rarer in DHTR circumstances, developed twice inside a brief interval. A historical past of transfusion and being pregnant in addition to preexisting irregular antibodies have been recognized as danger components for DHTR. Thus, extra consideration must be paid to the danger of DHTR redevelopment by repeated transfusions.

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